CVS targets EpiPen with cheaper generic version

CVS Health said Thursday that it would sell a generic version of an EpiPen competitor for a lower list price in a bid to tap into a groundswell of public resentment over skyrocketing drug costs, including attacks by President-elect Donald Trump.

The nation’s largest drug-store chain said Thursday that it would sell the generic version of Impax Laboratories’ Adrenaclick treatment for $109.99 per two-pack before potential discounts, or about one-third the initial $300 list price of pharmaceutical giant Mylan’s new generic EpiPen.

The move comes amid public consternation over multiple price increases that left the brand-name allergic-reaction treatment EpiPen with a list price of more than $600, up from about $100 in 2009.

Trump attacked drugmakers on Wednesday for sharp hikes in drug prices. Outrage over steep increases and the corresponding profit boon for drugmakers is one of few bipartisan matters in Washington, although disagreements over how to address the matter have prevented action.

"They're getting away with murder," Trump said Wednesday of drug companies, whose stocks plunged afterward.

The CVS move also comes amid scrutiny over the role of pharmacy benefit managers, or PBMs, such as the CVS Caremark unit, in contributing to EpiPen increases. The National Community Pharmacists Association recently called for a Congressional hearing on how pharmacy benefit managers have contributed to the "absurdly high" price.

In addition, the development heightens tension between pharmacy benefits managers, such as CVS Caremark, and drug giants, which blame each other in part for skyhigh drug prices.

CVS Pharmacy President Helena Foulkes said the company responded after its pharmacists heard a steady stream of concerns from customers over EpiPen’s price increases.

The epinephrine injector treats allergic reactions in potentially life-threatening situations. Adrenaclick, approved by the Food and Drug Administration in 2003, also administers epinephrine but through a slightly different injection.

In a business often shrouded in uncertainty over pricing, the CVS decision to target Mylan reflects an unusually public attack by a pharmacy giant on an individual pharmaceutical company.

But the chain, which operates more than 9,600 pharmacies, may have financial incentives to make a play against EpiPen.

Beyond generating publicity for siding with aggrieved customers, the company's PBM negotiates pricing with drug companies and may be seeking to tip the balance of power in its favor. Caremark manages prescription drugs through more than 68,000 retail pharmacies, including its own, as well as mail-order operations.

CVS faces "competitive pressures" in the pharmacy benefits management sector that have prompted "a larger portion of rebates and/or discounts," the chain said in a public filing Nov. 8.

The company recentlly warned that it would lose more than 40 million retail prescriptions in 2017 for several reasons, including competitor Walgreens' new mail-order pharmacy tie-up with Prime Therapeutics.

Pharmacy benefits managers are also under the microscope for their own role in drug price increases. New restrictions on benefits coverage by CVS preclude coverage for what it calls "hyperinflation" drugs and generic alternatives to specialty medicines, called biosimilars, according to drug-coupon service GoodRx.

Caremark now excludes 130 prescriptions from insurance coverage, making it the “most restrictive provider going into 2017,” GoodRx said in August.

Asked whether the Impax deal reflects an attempt to bolster Caremark's bargaining position, Foulkes did not address the matter. She also declined to reveal financial details of the company’s deal with Impax or to say whether CVS is siding with Trump on drug prices.

“Our focus has always been on finding solutions for patients first and foremost,” she said. “The best thing that can happen to keep drug prices low is to have a lot of competition in the marketplace.”

Mylan, for its part, has repeatedly argued that most customers don’t pay the full price of EpiPen out of pocket, with many relying on insurance or special manufacturer’s coupons. Still, the company introduced a generic version of its own treatment in December amid swirling scrutiny over profit taking. The company also offers rebates for certain patients and has said that about 85% of EpiPen users pay less than $100 out of pocket.

Foulkes said “in most cases” customers will qualify for a manufacturer’s coupon for $100 off the Adrenaclick treatment, making it $9.99 for them. She said Medicaid and Medicare plan members won’t qualify for the coupon but that CVS pharmacists will work with customers to identify their cheapest route to acquiring the treatment.

“We really think it solves this pain point in a very specific way and brings the cost down dramatically,” she said.

The deal also reflects a sharp price cut compared to certain CVS competitors. For example, Adrenaclick could be found in Walmart and Sam’s Club stores in August for $142 with a GoodRx coupon, according to Consumer Reports.

Adrenaclick will be available at all CVS Pharmacy locations starting Thursday. Foulkes said CVS would continue to sell EpiPen to customers who want the assurance of the brand-name product, though Mylan itself has said the generic version is identical to the brand-name product.

A pharmacist holds a package of EpiPen epinephrine auto-injectors in Sacramento, Calif., July 8, 2016. (Credit: AP)

CVS cuts the price of a generic EpiPen competitor in half

CVS is now selling a rival, generic version of Mylan's life-saving allergy treatment EpiPen at about a sixth of EpiPen’s price, months after Mylan was eviscerated before Congress because of EpiPen’s soaring cost.

The drugstore chain says it will charge $109.99 for a two-pack of the authorized generic version of Adrenaclick, a lesser-known treatment compared to EpiPen, which can cost more than $600.

CVS Health Corp., the nation's second-largest drugstore chain, says it cut the price it charges for the generic version of Adrenaclick nearly in half. The lower-priced product is now available at all CVS stores. The chain runs about 9,600 retail pharmacies in the United States, including several locations inside Target stores.

These treatments are stocked by schools and parents of children with severe allergies. They are used in emergencies to stop anaphylaxis, potentially fatal allergic reactions to insect bites and stings and to foods such as nuts and eggs.

The syringes are filled with the hormone epinephrine, and they expire after a year. That often means patients must fill new prescriptions even if they never used the old one.

Mylan started taking heat late last summer for its EpiPen pricing, which has climbed more than 500% since 2007. A congressional panel grilled Chief Executive Heather Bresch in September about the soaring cost, which she has blamed in part on insurers, pharmacy benefits managers and others in the supply chain between the drugmaker and the customer.

Bresch is one of several pharmaceutical executives who have been called before Congress, where both Republicans and Democrats have demanded explanations for spiraling drug prices that can plunge patients into debt or force them to skip prescriptions.

President-elect Donald Trump said Wednesday during a news conference that he wants to create new bidding procedures on drugs to save money.

Shares of most drugmakers sank almost immediately after his comments and were still under pressure Thursday. Mylan’s stock fell 1.4% on Thursday to $36.77. Meanwhile, shares of Impax Laboratories Inc. — the Hayward, Calif., company that makes Adrenaclick — rose 2.8% to $12.75.

In the aftermath of the unwanted attention, Mylan has expanded the financial aid it offers customers and launched its own authorized generic in December, priced around $300 per two-pack. But patients with no health insurance or with high-deductible insurance plans are exposed to the full price of the drug if they aren't aware of that assistance or if they don't seek it.

CVS says the new price it is charging for the Adrenaclick generic applies both to insured patients and to those who pay cash without coverage. It's what customers will pay at the pharmacy counter.

Prescription drug prices vary widely because of negotiations between pharmacies, drugmakers and pharmacy benefit managers. The new price CVS announced Thursday is lower, in some cases by more than $100, than other prices listed on websites such as GoodRx that compare retailers.

Impax Laboratories also offers a coupon program for Adrenaclick that can provide additional price breaks if a patient qualifies.

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