Acanthosis Nigricans is a non infectious and usually non destructive skin pigmentation disorder. However, this condition can be a sign of mild to severe health problems. Acanthosis Nigricans are characterized by dark, thickened, and textured skin folds such as velvet. This area of skin leaves a bad odor and itching on the skin. Acanthosis Nigricans - Alodokter_compress
The Cause of Acanthosis Nigricans
It is not known exactly the cause of nantric acanthosis, but generally this condition is associated with insulin resistance. Here are a number of causes of nantric akantosis:
- Obesity. Acanthosis Nigricans usually appear as a result of obesity. The more severe, the higher the risk of suffering nigrikans akantosis.
- Insulin resistance. This condition causes the body can not use insulin properly. Insulin is a hormone produced in the pancreas to control blood sugar levels. Insulin resistance is the cause of type 2 diabetes and most people with nigrikans akantosis also have insulin resistance.
- Use of drugs and supplements. Acanthosis Nigricans can be caused by the use of drugs and supplements such as oral contraceptives (Pill), corticosteroids such as prednisone, and niacin in high doses.
- Hormonal abnormalities. Acanthosis Nigricans can occur in people with hormonal disorders such as hypothyroidism (less active thyroid gland), ovarian cyst patients, and in patients with reduced production of hormones in the adrenal gland ( Addison's disease )
- Cancer. Acanthosis Nigricans can occur in cancer patients such as lymphoma or other tumors in the internal organs. Generally tumors of the stomach, liver, and colon (colon).
- Pituitary gland disorders ( pituitary ) in the brain.
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Symptoms of Acanthosis Nigricans
The symptoms of nigrikans akantosis are characterized by areas of gray-brown, darkened or darker skin of surrounding skin. The skin condition in this area is dry, itchy, and roughly textured like velvet. The areas of skin commonly affected by nigricantic acanthosis are:
- Fold the thighs.
- Soles of the feet.
Doctors can recognize nigrikans akantosis through direct observation to the patient's skin. Generally the doctor will check whether the patient has diabetes or insulin resistance, through a blood sugar test or insulin test by fasting first. In addition, a patient's medical history was also examined, including a history of supplemental consumption of vitamins and minerals, or muscle mass-forming supplements. In rare cases, the physician will take a small sample of the skin piece (biopsy) exposed to nigricantic acanthosis to be examined in the laboratory. In unknown nigricant acantosis, the doctor recommends blood tests and other tests to confirm the cause.
Treatment of Akanrosis Nigrikans
Treatment of nigrikans akantosis aims to address the cause of nigricantic acanthosis. Doctors will generally recommend treatment in the form of:
- Weight loss.
- Consumption of drugs to improve hormone levels in the body if akntosis nigrikans caused by hormonal disorders.
- Giving blood sugar-lowering drugs when you have diabetes.
- Surgery, chemotherapy, or radiotherapy for people with cancer.
- Skin lightening cream containing alpha hydroxy acid, salicylic acid, and urea.
- Antibiotic cream.
- Antibacterial soap.
- Acne drinking drugs such as isotretinoin and antibiotics.
- Laser therapy that focuses the rays fired to improve the appearance of the skin.
Complications of Nigerian toxicity
The complications of nigrikans akantosis depend on the cause. Dictatosis that arises as an adult needs to find out the cause. Insulin resistance and type 2 diabetes are most commonly associated with Acanthosis Nigricans, but the possibility of cancer should not be ignored.
Prevention of Nigerian toxicity
Acanthosis Nigricans not merely skin disorders. To prevent this, is to prevent the cause, including:
- Reduce excess body weight or obesity, for example by eating a good diet and regular exercise.
- Replace certain drugs that can trigger the onset of nigrikans akantosis. Consult a physician regarding the replacement of drugs.