Real Madrid went two points clear after a win over Eibar on Saturday afternoon but if Luis Enrique's side get all three points they will leapfrog their bitter rivals.
And in the first game since Luis Enrique announced he was leaving Barca will be looking for a repeat of last season's 6-1 win over Celta.
Barca 5-0 Celta player ratings
Barcelona ran riot at the Nou Camp in the first game since Luis Enrique announced he was leaving.
Lionel Messi scored twice and got two assists as Barca smashed Celta Vigo 5-0.
Neymar, Samuel Umtiti and Ivan Rakitic got the others in one of the most on-sided games of the season.
Messi was everywhere and Celta couldn’t handle him, but what rating did he get from Rik Sharma at the Nou Camp? (Hint: it’s a very, very good one)
FULL TIME: Barcelona 5-0 Celta
And that’s it, Barca win 5-0 and return to the top of the La Liga table.
It was never in doubt really was it?
That’s 20 games they have taken the lead in this season and they haven’t lost a single one, winning an impressive 18.
It was vintage Messi; scoring two, setting up two and generally being unplayable.
Your move, Real Madrid...
Nearly 6 against Celta again as Denis Suarez meets Messi’s lobbed pass with a header but Sergio gets in a rare save.
Barca still pushing for another goal here.
Don’t they ever give up?
Down the other end Aspas does well to create a chance for himself but fires the ball wide. Not his night.
Time to rest some legs.
Sergi Roberto is taken off for Andres Iniesta, who immediately takes the captain’s armband from Lionel Messi.
And Denis Suarez comes on for Neymar, who gets a standing ovation for his performance and that first-half goal.
Seriously, track it down on Twitter or something somewhere because it’s outrageous.
Also earlier on Busquets went off for Mascherano. I was halfway through typing it before Messi scored the fifth.
There’s only one man who is up for Man of the Match tonight.
Messi has two goals and two assists, and has quite frankly run the show tonight.
This is vintage Messi.
League Video Highlights: FC Barcelona vs Celta
Luis Enrique's team warmed up for the challenge of their last 16 Champions League second leg against Paris Saint-Germain in the bets possible way with a resounding 5-0 victory over Celta Vigo at Camp Nou. Leo Messi scored two brilliant goals, Neymar's goal is not to be missed, Umtiti grabbed his first as a Barça and Ivan Rakitic rounded off the scoring against the Galicians. Catch all the goals and more in our highlights video not just from this game but from the whole season!
La Liga: Magnificent Messi stars as Barcelona rout Celta Vigo, Real Madrid thrash Eibar
Lionel Messi was in inspired form as champions Barcelona hammered Celta Vigo 5-0 on Saturday, recording a fourth straight league victory which keeps them top of La Liga after Real Madrid had put the pressure on the Catalans with a 4-1 win at Eibar.
Messi opened the scoring in the 24th minute after a stunning solo run and then laid on a pass for Neymar to double the lead in the 40th with an irresistible chip.
Ivan Rakitic and Samuel Umtiti added to the scoring in the second half, the latter netting for the first time for the club, as Barca produced one of their best performances of the season in their first game since Luis Enrique revealed he would not be continuing as coach after the summer.
Messi then capped his virtuoso display with a darting run forward into the box past two defenders and a classy low finish, scoring an eighth goal in six league games and rounding off a rampant Barca display reminiscent of their 6-1 thrashing of Celta last year.
By the end of the game the words “Yes we can” echoed round the cavernous Nou Camp stadium as Barca’s fans began to dare to believe they could replicate this stunning display against Paris St Germain in the Champions League on Wednesday, when they need to overturn a four-goal deficit from the last 16 first leg, something no team has done in the competition’s history.
“It was a very complete performance, everyone was enjoying themselves. Everyone shone, everyone played at the top of their game and when that happens you’re able to score five goals and maybe we could have got more,” Luis Enrique told reporters.
“The PSG game will be nothing like today’s as the teams are so different but confidence is everything. It looks like a lost cause but if we do things well who knows what could happen? We’re going to keep trying until the last minute.”
Barca top the La Liga standings on 60 points, one ahead of Real, while third-placed Sevilla, on 55, visit Alaves on Monday.
Real Lift Confidence
Real Madrid overcame the absence of Gareth Bale and Cristiano Ronaldo to romp to victory at Eibar, recording their biggest win since beating Real Sociedad 3-0 in January, lifting their confidence after dropping five points in three games.
Karim Benzema was the focal point in Real’s attack without the suspended Bale and injured Ronaldo and fired the visitors ahead in the 14th minute, following up his own shot on the rebound, before stretching their advantage in the 25th.
James Rodriguez provided the cross for Benzema’s second goal and the Frenchman returned the favour for his Colombian team mate to net his first league goal since September in the 29th minute.
Marco Asensio hit the fourth on the hour with a rebound after James had struck the post, although Ruben Pena bundled in a consolation goal for Eibar in the 72nd minute.
“It was a very good reaction, we scored three times in the space of half an hour. We knew it was a difficult ground to go to but we scored early and gave a serious display,” Zidane told reporters.
“All sorts of things happen during a season and a team can’t always play well, but we did very well today and played with a lot of intensity. We made a flying start and that was very important. We know that there’s still a long way to go.”